Measurement of bone marrow lesions by MR imaging in knee osteoarthritis using quantitative segmentation methods – a reliability and sensitivity to change analysis

Table 4 The 95% limits of inter-observer agreement of relative BML volumes at baseline

95% limits of agreement
Area	Segmentation method	Inter-/intra-observer agreement	95 % limits of agreement
Femur	CAS	Inter-observer	-2.0	1.8
Femur	Manual	Inter-observer	-6.5	6.2
Tibia	CAS	Inter-observer	-4.5	4.7
Tibia	Manual	Inter-observer	-6.9	8.2

CAS = computer assisted segmentation.
Based on the 22 baseline examinations used to determine sensitivity to change over time.

ISSN: 1471-2474