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Figure 3 | BMC Musculoskeletal Disorders

Figure 3

From: Measurement of bone marrow lesions by MR imaging in knee osteoarthritis using quantitative segmentation methods – a reliability and sensitivity to change analysis

Figure 3

Sagittal STIR image medially in the same 61-year-old female as shown in Figure 2 . (a, b) The posterior femoral region is delineated via points A-C. There are ill-defined increased SI areas in the bone marrow (bone marrow lesion (BML)) of the medial femoral condyle as part of medial osteoarthritis (OA). (b) The manually segmented area of BML with SIs above the threshold value (219) was 334 mm2 being finally adjusted by measuring the SIs along the segmentation borders using a small rectangular area (arrow). (c, d) The computer assisted segmentation (CAS) of the BMLs is shown with a threshold corresponding to the mean SI plus 1 SD (c) and 2 SDs (d), respectively. The shape and extend of the area of pixels above the threshold displayed in (d) corresponds better to the area of manual segmentation (b) than the area in (c), 183 mm2 and 304 mm2, respectively.

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