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Table 2 Mean PA28 γ level (ng/ml), standard deviations (SD), minimum (min.) and maximum (max.) values from patients with different diseases

From: Increased proteasome activator 28 gamma (PA28γ) levels are unspecific but correlate with disease activity in rheumatoid arthritis

Disease n mean SD min. max. PA28γpositive P value
Healthy 20 17.5 7.4 1.4 29.6 0.0% (0/20)  
Cancer 28 39.6 72.7 11.9 407.8 10.7% (3/28) **0.003
RA 104 37.6 33.5 0.0 205.8 26.9% (28/104) **0.0002
SS 34 37.1 36.1 0.0 195.2 29.4% (10/34) **0.008
AOSD 15 23.8 11.9 12.4 52.9 13.3% (2/15) 0.142
CTD:        
Polymyositis 18 31.1 21.2 6.7 85.4 22.2% (4/18) *0.033
SLE 37 60.0 127.7 0.0 636.6 24.3% (9/37) 0.432
UCTD 11 35.9 15.4 18.4 61.7 36.4% (4/11) **0.001
total CTD 66 48.1 96.8 0.0 636.6 25.8% (17/66) *0.040
  1. Data over the calculated cutoff are defined as PA28γ positive. P values represent significance (*, P & 0.05 and **, P & 0.01) compared with healthy control group. AOSD; adult-onset Still’s disease, CTD; different connective-tissue diseases, RA; rheumatoid arthritis SLE; systemic lupus erythematosus, SS; Sjögren’s syndrome, UCTD; undifferentiated connective-tissue disease.