Disease
|
n
|
mean
|
SD
|
min.
|
max.
|
PA28γpositive
|
P value
|
---|
Healthy
|
20
|
17.5
|
7.4
|
1.4
|
29.6
|
0.0% (0/20)
| |
Cancer
|
28
|
39.6
|
72.7
|
11.9
|
407.8
|
10.7% (3/28)
|
**0.003
|
RA
|
104
|
37.6
|
33.5
|
0.0
|
205.8
|
26.9% (28/104)
|
**0.0002
|
SS
|
34
|
37.1
|
36.1
|
0.0
|
195.2
|
29.4% (10/34)
|
**0.008
|
AOSD
|
15
|
23.8
|
11.9
|
12.4
|
52.9
|
13.3% (2/15)
|
0.142
|
CTD:
| | | | | | | |
Polymyositis
|
18
|
31.1
|
21.2
|
6.7
|
85.4
|
22.2% (4/18)
|
*0.033
|
SLE
|
37
|
60.0
|
127.7
|
0.0
|
636.6
|
24.3% (9/37)
|
0.432
|
UCTD
|
11
|
35.9
|
15.4
|
18.4
|
61.7
|
36.4% (4/11)
|
**0.001
|
total CTD
|
66
|
48.1
|
96.8
|
0.0
|
636.6
|
25.8% (17/66)
|
*0.040
|
- Data over the calculated cutoff are defined as PA28γ positive. P values represent significance (*, P & 0.05 and **, P & 0.01) compared with healthy control group. AOSD; adult-onset Still’s disease, CTD; different connective-tissue diseases, RA; rheumatoid arthritis SLE; systemic lupus erythematosus, SS; Sjögren’s syndrome, UCTD; undifferentiated connective-tissue disease.