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Table 2 Mean PA28 γ level (ng/ml), standard deviations (SD), minimum (min.) and maximum (max.) values from patients with different diseases

From: Increased proteasome activator 28 gamma (PA28γ) levels are unspecific but correlate with disease activity in rheumatoid arthritis

Disease

n

mean

SD

min.

max.

PA28γpositive

P value

Healthy

20

17.5

7.4

1.4

29.6

0.0% (0/20)

 

Cancer

28

39.6

72.7

11.9

407.8

10.7% (3/28)

**0.003

RA

104

37.6

33.5

0.0

205.8

26.9% (28/104)

**0.0002

SS

34

37.1

36.1

0.0

195.2

29.4% (10/34)

**0.008

AOSD

15

23.8

11.9

12.4

52.9

13.3% (2/15)

0.142

CTD:

       

Polymyositis

18

31.1

21.2

6.7

85.4

22.2% (4/18)

*0.033

SLE

37

60.0

127.7

0.0

636.6

24.3% (9/37)

0.432

UCTD

11

35.9

15.4

18.4

61.7

36.4% (4/11)

**0.001

total CTD

66

48.1

96.8

0.0

636.6

25.8% (17/66)

*0.040

  1. Data over the calculated cutoff are defined as PA28γ positive. P values represent significance (*, P & 0.05 and **, P & 0.01) compared with healthy control group. AOSD; adult-onset Still’s disease, CTD; different connective-tissue diseases, RA; rheumatoid arthritis SLE; systemic lupus erythematosus, SS; Sjögren’s syndrome, UCTD; undifferentiated connective-tissue disease.