Figure 2From: Increased proteasome activator 28 gamma (PA28γ) levels are unspecific but correlate with disease activity in rheumatoid arthritis Circulating PA28γ levels in human sera. A) Scatter dot plot of circulating PA28γ serum levels measured by sandwich ELISA in patients with cancer (n = 28), rheumatoid arthritis (RA, n = 104), Sjögren’s syndrome (SS, n = 34), adult onset Still’s disease (AOSD, n = 15) and different connective-tissue diseases (CTD, n = 66) compared with healthy controls (n = 20). Dashed line indicates the calculated cutoff value for positive response of 39.8 ng/ml PA28γ as the mean plus 3-fold standard deviation of healthy controls. The results are represented as mean PA28γ levels of duplicate wells. Medians are shown as grey lines. P-values as indicated compared with healthy control. n.s., not significant. B) Frequency of different PA28γ serum levels in healthy and pathological subjects.Back to article page