| Inflammation (ankle diameter) | Pain (withdrawal threshold) | ||
---|---|---|---|---|
Prophylactic | Therapeutic | Prophylactic | Therapeutic | |
Etanercept 0.25 mg/kg | 70% (P < 0.001) | 44% (P < 0.001) | 37% (P < 0.05) | 0% (ns) |
Etanercept 1.0 mg/kg | 76% (P < 0.001) | 52% (P < 0.001) | 24% (ns) | 0% (ns) |
Dexamethasone | nd | 84% (P < 0.001) | nd | 39% (P < 0.05) |