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Table 1 Cellular phenotyping of neutrophils and T cells in local and systemic compartments^

From: Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis

Tissue

Cell type

Non-arthritic

Flare 1 (24 hr post i.a. injection)

Flare 2 (24 hr post i.v. injection)

Ankle joint

Neutrophils

3561

6.4* 105

5.6* 104

CD3+ T cells

1413

1.6* 105

2.6* 104

Lymph node

Neutrophils

BLQ

BLQ

BLQ

 

CD3+ T cells

9.1* 106

10.1* 106

19.9* 106

  1. ^The total number of cells in the injected ankle joint and lymph node compartments as ascertained by flow cytometry using methods described above. Values calculated from pooled tissue samples (n = 4 animals/group). BLQ: Below the Level of Quantification.