Population | Comparison (Na) | Test of association | Test of heterogeneity | ||
---|---|---|---|---|---|
 |  | OR (95% CI) | P b | P c | I 2(%) |
Overall | C vs. T (20) | 0.85 (0.80-0.90) | 0.000 | 0.019 | 44.1 |
 | CC vs. TT (17) | 0.73 (0.66-0.81) | 0.000 | 0.328 | 10.8 |
 | CT vs. TT (17) | 0.84 (0.76-0.94) | 0.002 | 0.000 | 62.2 |
 | CC/CT vs. TT (17) | 0.81 (0.73-0.90) | 0.000 | 0.000 | 61.7 |
 | CC vs. CT/TT (17) | 0.81 (0.74-0.86) | 0.000 | 0.623 | 0.0 |
Ethnicity | Â | Â | Â | Â | Â |
Asian | C vs. T (6) | 0.78 (0.67-0.92) | 0.003 | 0.006 | 69.5 |
 | CC vs. TT (6) | 0.60 (0.48-0.76) | 0.000 | 0.333 | 12.9 |
 | CT vs. TT (6) | 0.80 (0.63-1.02) | 0.071 | 0.002 | 74.3 |
 | CC/CT vs. TT (6) | 0.76 (0.60-0.96) | 0.021 | 0.001 | 75.8 |
 | CC vs. CT/TT (6) | 0.68 (0.56-0.84) | 0.000 | 0.494 | 0.0 |
Caucasian | C vs. T (14) | 0.87 (0.82-0.92) | 0.000 | 0.229 | 20.7 |
 | CC vs. TT (11) | 0.78 (0.70-0.87) | 0.000 | 0.611 | 0.0 |
 | CT vs. TT (11) | 0.86 (0.76-0.97) | 0.012 | 0.011 | 56.2 |
 | CC/CT vs. TT (11) | 0.83 (0.75-0.93) | 0.001 | 0.020 | 52.6 |
 | CC vs. CT/TT (11) | 0.84 (0.76-0.93) | 0.001 | 0.822 | 0.0 |
Sex | Â | Â | Â | Â | Â |
Females | C vs. T (9) | 0.85 (0.78-0.93) | 0.000 | 0.236 | 23.3 |
 | CC vs. TT (9) | 0.73 (0.62-0.87) | 0.000 | 0.923 | 0.0 |
 | CT vs. TT (9) | 0.81 (0.69-0.95) | 0.011 | 0.029 | 53.2 |
 | CC/CT vs. TT (9) | 0.80 (0.69-0.93) | 0.003 | 0.039 | 50.7 |
 | CC vs. CT/TT (9) | 0.83 (0.70-0.97) | 0.021 | 0.990 | 0.0 |
Males | C vs. T (9) | 0.85 (0.74-0.97) | 0.020 | 0.171 | 30.9 |
 | CC vs. TT (9) | 0.65 (0.50-0.84) | 0.001 | 0.464 | 0.0 |
 | CT vs. TT (9) | 0.99 (0.81-1.20) | 0.888 | 0.139 | 34.8 |
 | CC/CT vs. TT (9) | 0.90 (0.74-1.09) | 0.272 | 0.107 | 39.1 |
 | CC vs. CT/TT (9) | 0.66 (0.51-0.84) | 0.001 | 0.613 | 0.0 |