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Table 4 Summary of findings of comparison III (multimodal proprioceptive Training (mPrT) versus inactive controls, educational approach or other exercise)

From: Effects of proprioceptive exercises on pain and function in chronic neck- and low back pain rehabilitation: a systematic literature review

Patient or population: adults with non-specific chronic low-back pain; Settings: primary and secondary health care centres

Outcomes

Illustrative means (95% CI)

N (studies)

GRADE

Comments

Control group

Intervention group

   

Comparison 3.1

Inactive control

mPrT

   

Pain intensity various scales short-term follow-up

 

The mean pain intensity in the intervention group was 0.55 standard deviations lower (0.98 to 0.13 lower)

329(4 studies)

+++04moderate

 

Pain intensity various scales long-term follow-up

 

The mean pain intensity in the intervention group was 0.36 standard deviations lower (0.65 to 0.08 lower)

247(2 studies)

++002,4 low

One additional study did not quantify this outcome but reported no difference between groups.

Back specific functional status various scales short-term follow-up

 

The mean functional status in the intervention group was 1.39 standard deviations lower (2.95 lower to 0.16 higher).

246 (2 studies)

++002,4 low

One additional study did not quantify this outcome but reported no difference between groups.

Back specific functional status various scales long-term follow-up

 

The mean functional status in the intervention group was 0.44 standard deviations lower (1.80 lower to 0.92 higher).

246 (2 studies)

+++02 moderate

One additional study did not quantify this outcome but reported no difference between groups.

Comparison 3.2

Other exercise

mPrT

N (studies)

GRADE

Comments

Pain intensity various scales short-term follow-up

 

The mean pain intensity in the intervention group was 0.40 standard deviations lower (0.84 lower to 0.05 higher)

465 (8 studies)

++002,4 low

 

Pain intensity various scales long-term follow-up

The mean pain intensity of the control group was 35.7 points.

The mean pain intensity in the intervention group of one study was 13.4 points higher (5.96 to 20.84 higher).

122 (1 studies)

++002,4 low

One additional study did not quantify this outcome but reported no difference between groups.

Back specific functional status various scales short-term follow-up

 

The mean pain intensity in the intervention group was 0.45 standard deviations lower (0.83 to 0.08 lower)

466 (8 studies)

++002,4 low

One additional study did not quantify this outcome but reported no difference between groups.

Back specific functional status various scales long-term follow-up

The mean pain intensity of the control group was 16.2 points.

The mean pain intensity in the intervention group of one study was 3.2 points higher (1.55 lower to 7.95 higher).

107 (1 studies)

++002,3 low

One additional study did not quantify this outcome but reported no difference between groups.

Comparison 3.3

Educational approach

mPrT

N (studies)

GRADE

Comments

Pain intensity VAS scales (0–10) short-term follow-up

The mean pain intensity of the control group was 4.9 points.

The mean pain intensity in the intervention group was 0.30 points higher (0.32 lower to 0.92 higher).

185 (1 study)

++002,3,§ low

 

Pain intensity various scales long-term follow-up

The mean pain intensity of the control group was 4.5 points.

The mean pain intensity in the intervention group was 0.30 points higher (0.40 lower to 1.00 higher).

164 (1 study)

++002,3,§ low

 

Back specific functional status LBP rating scale short-term follow-up

The mean score on the LBP rating scale of the control group was 11.6 points.

The mean pain intensity in the intervention group was 1.40 points higher (0.33 lower to 3.13 higher).

185 (1 study)

++002,3,§ low

 

Back specific functional status LBP rating scale long-term follow-up

The mean score on the LBP rating scale of the control group was 11.0 points.

The mean pain intensity in the intervention group was 2.00 points higher (0.06 to 3.94 higher).

164 (1 study)

++002,3,§ low

 
  1. N = total number of patients; CI = Confidence Interval; 1Serious limitations in study design (i.e. >25% of participants from studies with high risk of bias); 2Serious imprecision (i.e. total number of participants <300 for each outcome or only one study available for comparison); 3Indirectness of population (e.g. only one study), intervention (applicability) and outcome measures; 4Serious inconsistency (i.e. significant statistical heterogeneity or opposite direction of effects). §Only one study, consistency cannot be evaluated.
  2. GRADE Working Group grades of evidence.
  3. High quality: Further research is very unlikely to change our confidence in the estimate of effect.
  4. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
  5. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
  6. Very low quality: We are very uncertain about the estimate.