Table 4 Pooled results of 3 SNPs in and around CHL1 gene in AIS in a Chinese Han population
Genotype | AIS (%) | Control (%) | P-value (χ2) | Alleles | AIS (%) | Control (%) | P-value (χ2) | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|
rs2272522 | ||||||||
CC | 140(28.0) | 110(22.0) | C | 518(51.8) | 481(48.1) | C vs. T | ||
CT | 238(47.6) | 261(52.2) | 0.08 | T | 482(48.2) | 519(51.9) | 0.09 | 1.16 (0.97-1.38) |
TT | 122(24.4) | 129(25.8) | ||||||
rs2055314 | ||||||||
CC | 217(43.4) | 220(44.0) | C | 670(67.0) | 663(66.3) | C vs. T | ||
CT | 236(47.2) | 223(44.6) | 0.50 | T | 330(33.0) | 337(33.7) | 0.74 | 1.03 (0.86-1.24) |
TT | 47(9.4) | 57(11.4) | ||||||
rs10510181 | ||||||||
GG | 144(28.8) | 149(29.8) | G | 519(51.9) | 542(54.2) | G vs. A | ||
GA | 231(46.2) | 244(48.8) | 0.39 | A | 481(48.1) | 458(45.8) | 0.30 | 0.91 (0.77-1.09) |
AA | 125(25.0) | 107(21.4) |