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Table 7 Association between incident vertebral fractures and mean change in OPAQ at endpoint

From: Psychometric properties of the osteoporosis assessment questionnaire (OPAQ) 2.0: results from the multiple outcomes of raloxifene evaluation (MORE) study

OPAQ Scales 0 Incident Vertebral Fracture (n =918) ≥ 1 Incident Vertebral Fracture (n =155) p-valuea
Walking/bending −1.33 ± 14.49 −5.22 ± 20.92 0.0071*
Standing/sitting 0.47 ± 17.40 −3.30 ± 22.35 0.0165*
Dressing/reaching −1.19 ± 16.73 −3.76 ± 21.91 0.1368
Household/self-care −0.90 ± 14.47 −5.42 ± 19.28 0.0012*
Transfers −0.29 ± 15.53 −3.45 ± 26.57 0.0489*
Usual work −1.12 ± 17.01 −6.09 ± 25.73 0.0011*
Fear of falls −3.00 ± 15.72 −3.90 ± 19.23 0.4339
Level of tension 0.96 ± 14.86 −1.78 ± 14.23 0.0449*
Body image −0.51 ± 22.01 −1.51 ± 25.67 0.8436
Independence −0.30 ± 14.96 −4.49 ± 19.72 0.0032*
Back pain 0.71 ± 18.76 −5.60 ± 25.46 0.0004**
Fatigue 1.11 ± 16.13 −0.33 ± 14.95 0.1862
Social activity 3.68 ± 19.84 3.19 ± 19.53 0.9628
Support, family and friends −0.01 ± 18.04 0.90 ± 19.46 0.4000
  1. Abbreviations: n = number; OPAQ = Osteoporosis Assessment Questionnaire.
  2. Results are shown as the mean ± standard deviation change from baseline to study endpoint.
  3. a p-values based on analysis of covariance model controlling for country of origin, age, body mass index (BMI), years since menopause, smoking status (yes vs. no), alcohol consumption (yes vs. no), and number of preexisting conditions.
  4. *p < 0.05; **p < 0.001.