Meta-analysis of tumor necrosis factor alpha -308 polymorphism and knee osteoarthritis risk

Table 1 Characteristics of studies included in TNF-α polymorphisms and osteoarthritis

Study	Ethnicity	Design	Phenotype	HWE	Total cases	Total controls	GG		GA		AA
Study	Ethnicity	Design	Phenotype	HWE	Total cases	Total controls	Cases	Controls	Cases	Controls	Cases	Controls
Moos 2000 [17]	Caucasian	HCC	Knee/Hip	No	55	240	36	166	18	74	1	0
Romero 2002 [18]	Caucasian	HCC	Knee	Yes	31	30	28	28	3	2	0	0
Sezgin 2008 [19]	Caucasian	HCC	Knee	Yes	151	84	121	72	26	12	4	0
Han 2012 [20]	Asian	PCC	Knee	Yes	301	291	79	258	188	33	34	0
Valle 2012 [21]	Caucasian	PCC	Knee	Yes	50	100	44	93	6	7	0	0
Ji 2013 [22]	Asian	PCC	Knee	Yes	200	305	143	253	50	50	7	2
Cheng 2013 [23]	Asian	PCC	Knee	Yes	200	305	143	253	50	49	7	3

HCC Hospital based case–control study, PCC population based case–control study. HWE Hardy-Weinberg equilibrium.

ISSN: 1471-2474