Figure 3
From: Novel COL9A3 mutation in a family diagnosed with multiple epiphyseal dysplasia: a case report
MD simulation of wild type and mutant model structure of trimer collagen. Wild type model structure (A), twisted form of the mutant (B), collagen-collagen interaction by a hydrogen bonding in wild type (C), the substitution of glycine to aspartic acid causing an interaction with the self strand (D), C-alpha distance between residues in wild type and mutant trimer (E and F), respectively, and energy plot of wild type and mutant collagen by Amber-GPU (G).