Figure 9

Effect of PAM treatment on MMP9 and TLR4 protein expression in cartilage and subchondral bone. Relative protein levels as measured by western blot are shown, (a) MMP9 protein expression in cartilage and (b) subchondral bone. (c) TLR4 protein expression in cartilage. * and ** indicate groups significantly different from the sham-operated rabbits treated with vehicle (*P <0.05 and **P <0.01). # and ## indicate significant differences between the ACLT group and rabbits treated with pamidronate. (# P <0.05 and ## P <0.01).