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Table 5 Multivariate associations of the inflammatory markers (ESR and CRP) with age, sex, and BMI after 1 year (N = 365)

From: How age and sex affect the erythrocyte sedimentation rate and C-reactive protein in early rheumatoid arthritis

Variables* Unstandardized coefficient Standardized coefficient p-value
  Beta (95% CI) Standard error Beta (95% CI)  
ESR model     
  TJC28 -0.024 (-0.056 – 0.008) 0.016 -0.088 (-0.206 – 0.031) 0.147
  SJC28 0.014 (-0.030 – 0.058) 0.022 0.035 (-0.074 – 0.144) 0.527
  General health 0.004 (0.000 – 0.008) 0.002 0.103 (-0.012 – 0.219) 0.080
  Female sex 0.370 (0.187 – 0.552) 0.093 0.213 (0.108 – 0.317) <0.001
  Age: 55-65 years 0.151 (-0.055 – 0.356) 0.105 0.084 (-0.031 – 0.198) 0.151
  Age: >65 years 0.570 (0.363 – 0.777) 0.105 0.320 (0.203 – 0.436) <0.001
  Overweight -0.349 (-0.581 – -0.117) 0.118 -0.207 (-0.345 – -0.069) 0.003
  Normal weight -0.283 (-0.520 – -0.045) 0.121 -0.164 (-0.302 – -0.026) 0.020
CRP model #     
  TJC28 -0.014 (-0.047 – 0.019) 0.017 -0.052 (-0.174 – 0.070) 0.405
  SJC28 -0.002 (-0.047 – 0.043) 0.023 -0.006 (-0.119 – 0.107) 0.917
  General health 0.007 (0.002 – 0.011) 0.002 0.179 (0.060 – 0.297) 0.003
  Age: 55-65 years 0.073 (-0.137 – 0.283) 0.107 0.041 (-0.077 – 0.159) 0.495
  Age: >65 years 0.292 (0.081 – 0.504) 0.107 0.165 (0.046 – 0.284) 0.007
  Overweight -0.257 (-0.494 – -0.020) 0.120 -0.154 (-0.296 - -0.012) 0.033
  Normal weight -0.328 (-0.571 – -0.085) 0.124 -0.192 (-0.335 - -0.050) 0.008
  1. *ESR = erythrocyte sedimentation rate, CRP = C-Reactive Protein, TJC28 = tender joint count in 28-joints, SJC28 = swollen joint count in 28-joints. CI = confidence interval. R2 ESR-model: 15.6%, R2 CRP model: 6.9%.
  2. #After 1 year, sex was no longer significantly associated with CRP levels (p = 0.855). Consequently, this factor is no longer included in the CRP model.