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Table 2 Area Under Curve (AUC) of Receiver Operating Characteristics (ROC) for prediction of vertebral fractures using FRAX tools and T-scores

From: The discriminative ability of FRAX, the WHO algorithm, to identify women with prevalent asymptomatic vertebral fractures: a cross-sectional study

 

VFs grade 2/3

VFs grade 1

 

AUC

p

AUC

p

FRAX major fracture without BMD

0.757 (0.718 – 0.797)

<0.0001

0.637 (0.591 – 0.683)

<0.0001

FRAX hip fracture without BMD

0.756 (0.716 – 0.796)

<0.0001

0.631 (0.585 – 0.677)

<0.0001

FRAX major fracture with BMD

0.736 (0.695 – 0.777)

<0.0001

0.662 (0.618 – 0.707)

<0.0001

FRAX hip fracture with BMD

0.748 (0.710 – 0.786)

<0.0001

0.662 (0.618 – 0.706)

<0.0001

Lumbar spine T-score

0.660 (0.611 – 0.708)*

<0.0001

0.610 (0.569 – 0.650)

<0.0001

Femoral neck T-score

0.707 (0.664 – 0.751)*

<0.0001

0.658 (0.621 – 0.695)

<0.0001

FRAX major fracture without BMD with parity

0.697 (0.643 – 0.751)*

<0.0001

0.632 (0.585 – 0.678)

<0.0001

  1. *Indicates p < 0.05 in comparison with the AUC of ROC of FRAX major fracture without BMD.