Figure 7
From: In vivo experimental intervertebral disc degeneration induced by bleomycin in the rhesus monkey
mRNA expression of genes at 15 months postoperatively. This graph showed a lower expression of aggrecan, Col2α1 and caveolin-1, and a significant upregulation of MMP-3, ADAMTS-5, TNF-α, IL-1β, IL-6 and TGF-β1 in the bleomycin group as compared with the control group (P < 0.05). The expression of vWF in the bleomycin group significantly decreased in comparison with the control group (P < 0.05). #P < 0.05 vs the control group.