Figure 1

Representative photographs of soleus muscles. A, C, E, and G show HE staining. B, D, F, and H show immunostained sections for PECAM-1. A and B show CONT sections; C and D show HS sections; E and F show HS + WB sections; and G and H show HS + VIB sections. In HS (C), marked muscle fiber atrophy was observed. Muscle fiber atrophy was also observed in HS + WB (E) and HS + VIB (G), but to a milder extent than that seen in HS. In HS (D), capillary number looked greatest because of marked muscle fiber atrophy, but actually the C/F ratio was the smallest. Scale bar: 100 μm; arrows: capillaries.