Table 2 Vascular parameters in non-arthritic and arthritic mice

TV [mm ³ ]

WT

10.6 ± 5.2

34.6 ± 4.9

59.6 ± 4.6

69.0 ± 7.0

hTNFtg

11.5 ± 3.1

40.0 ± 11.3

66.0 ± 13.4

78.4 ± 14.4

VV/TV [%]

WT

5.9 ± 3.1

2.0 ± 0.6²

1.1 ± 0.5¹

1.4 ± 0.5²

hTNFtg

3.7 ± 1.8

3.2 ± 0.7

1.8 ± 0.4

2.4 ± 0.3

VS [mm ² ]

WT

6.2 ± 3.7

8.4 ± 3.0²

9.4 ± 3.8¹

12.5 ± 5.0²

hTNFtg

6.0 ± 1.9

18.7 ± 7.9

16.0 ± 5.6

22.3 ± 5.4

V.Th _3D [μm]

WT

81.4 ± 19.5¹

71 ± 14.6

56.2 ± 10.2

57.4 ± 7.1

hTNFtg

59.0 ± 13.9

61 ± 9.1

65.0 ± 21.5

64.0 ± 6.5

V.N _2D [1/mm]

WT

1.4 ± 0.3

0.9 ± 0.2³

0.8 ± 0.1²

0.8 ± 0.1²

hTNFtg

1.6 ± 0.2

1.5 ± 0.2

1.0 ± 0.1

1.0 ± 0.1

V.Sp _2D [mm]

WT

0.6 ± 0.2

0.9 ± 0.2³

1.1 ± 0.2²

1.1 ± 0.2¹

hTNFtg

0.5 ± 0.1

0.6 ± 0.1

0.9 ± 0.1

0.8 ± 0.1