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Table 2 Vascular parameters in non-arthritic and arthritic mice

From: Characterization and quantification of angiogenesis in rheumatoid arthritis in a mouse model using μCT

  VOI 1 VOI 2 VOI 3 VOI 4
TV [mm 3 ] WT 10.6 ± 5.2 34.6 ± 4.9 59.6 ± 4.6 69.0 ± 7.0
hTNFtg 11.5 ± 3.1 40.0 ± 11.3 66.0 ± 13.4 78.4 ± 14.4
VV/TV [%] WT 5.9 ± 3.1 2.0 ± 0.62 1.1 ± 0.51 1.4 ± 0.52
hTNFtg 3.7 ± 1.8 3.2 ± 0.7 1.8 ± 0.4 2.4 ± 0.3
VS [mm 2 ] WT 6.2 ± 3.7 8.4 ± 3.02 9.4 ± 3.81 12.5 ± 5.02
hTNFtg 6.0 ± 1.9 18.7 ± 7.9 16.0 ± 5.6 22.3 ± 5.4
V.Th 3D [μm] WT 81.4 ± 19.51 71 ± 14.6 56.2 ± 10.2 57.4 ± 7.1
hTNFtg 59.0 ± 13.9 61 ± 9.1 65.0 ± 21.5 64.0 ± 6.5
V.N 2D [1/mm] WT 1.4 ± 0.3 0.9 ± 0.23 0.8 ± 0.12 0.8 ± 0.12
hTNFtg 1.6 ± 0.2 1.5 ± 0.2 1.0 ± 0.1 1.0 ± 0.1
V.Sp 2D [mm] WT 0.6 ± 0.2 0.9 ± 0.23 1.1 ± 0.22 1.1 ± 0.21
  hTNFtg 0.5 ± 0.1 0.6 ± 0.1 0.9 ± 0.1 0.8 ± 0.1
  1. TV: total volume; VV: vessel volume; VS vessel surface; V.Th3D: vessel thickness; V.N2D: vessel number; V.Sp2D: vessel spacing; WT: wild type mice; hTNFtg: human tumor necrosis factors transgenic mice.
  2. 10.01 ≤ p < 0.05. 20.001 ≤ p <0.01; 3p < 0.001.