Characterization and quantification of angiogenesis in rheumatoid arthritis in a mouse model using μCT

Table 1 Parameters to quantify vascularization

Model independent direct 3D parameters
Vessel density (vessel volume per total volume)	VV/TV
Vessel surface	VS
Vessel thickness	V.Th _3D
Rod-model based parameters
Vessel thickness	$V . T h_{2 D} = 4 / (\frac{VS}{VV})$
Vessel spacing	$V . S p_{2 D} = V . T h_{2 D} \cdot (\sqrt{\frac{4 / π \cdot TV}{VV}} - 1)$
Vessel number	$V . N_{2 D} = \sqrt{(\frac{4}{π} \cdot \frac{VV}{TV}) / V . T h_{2 D}}$

ISSN: 1471-2474