Table 3 Sensitivity, specificity and area under Receiver Operating Characteristics curve (ROC-area) of index test
Standard references | ||||||
|---|---|---|---|---|---|---|
Historic fulfilment of ACR 1987 criteria | Diagnosis by rheumatologist | |||||
Sensitivity | Specificity | ROC-area | Sensitivity | Specificity | ROC-area | |
ACR 1987 criteria | ||||||
50 (27-73) | 100 (89-100) | 75 (64-86) | 44 (22-69) | 94 (81-99) | 69 (57-82) | |
Adapted ACR 1987 criteria (GS synovitis, US erosions, ACPA) | ||||||
75 (51-91) | 97 (84-100) | 86 (76-96) | 72 (47-90) | 91 (77-98) | 82 (70-93) | |
Adapted ACR 1987 criteria (GS synovitis, US erosions, RF) | ||||||
75 (51-91) | 94 (80-99) | 84 (74-95) | 72 (47-90) | 87 (73-97) | 80 (68-92) | |
Adapted ACR 1987 criteria (GS synovitis, erosions on radiography, ACPA) | ||||||
60 (36-81) | 97 (84-100) | 79 (67-91) | 56 (31-79) | 91 (77-98) | 73 (61-86) | |
Adapted ACR 1987 criteria (PD synovitis, US erosions, ACPA) | ||||||
35 (15-59) | 100 (89-100) | 67 (57-78) | 39 (17-64) | 100 (90-100) | 69 (58-81) | |
RAMRIS scale for synovitis | ||||||
MCP joints 2-5 (cut-off ≥5) | 62 (32-86) | 94 (73-100) | 78 (63-93) | 69 (39-91) | 100 (73-100) | 85 (72-98) |
Combined wrist and MCP joints 2-5 (cut-off ≥10) | 62 (32-86) | 94 (73-100) | 78 (63-93) | 62 (32-86) | 94 (73-100) | 78 (63-93) |