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Table 3 Full-length KIR2DS4 interaction in MTX response dependent on bone erosion and rheumatoid factor presence

From: Presence of the full-length KIR2DS4 gene reduces the chance of rheumatoid arthritis patients to respond to methotrexate treatment

MTX responsiveness Frequency (good responders/all)
ED RF 2DS4f presence 2DS4f absence
+ + 36.2 (21/58) 43.6 (48/110)
+ - 70.0 (14/20) 76.7 (33/43)
- + 72.7 (8/11) 72.4 (21/29)
- - 75.0 (12/16) 88.0 (22/25)
  1. +, clinical factor detected; -, clinical factor absent.