From: Presence of the full-length KIR2DS4 gene reduces the chance of rheumatoid arthritis patients to respond to methotrexate treatment
MTX responsiveness
Frequency (good responders/all)
ED
RF
2DS4f presence
2DS4f absence
+
36.2 (21/58)
43.6 (48/110)
-
70.0 (14/20)
76.7 (33/43)
72.7 (8/11)
72.4 (21/29)
75.0 (12/16)
88.0 (22/25)