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Table 3 Full-length KIR2DS4 interaction in MTX response dependent on bone erosion and rheumatoid factor presence

From: Presence of the full-length KIR2DS4 gene reduces the chance of rheumatoid arthritis patients to respond to methotrexate treatment

MTX responsiveness

Frequency (good responders/all)

ED

RF

2DS4f presence

2DS4f absence

+

+

36.2 (21/58)

43.6 (48/110)

+

-

70.0 (14/20)

76.7 (33/43)

-

+

72.7 (8/11)

72.4 (21/29)

-

-

75.0 (12/16)

88.0 (22/25)

  1. +, clinical factor detected; -, clinical factor absent.