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Table 3 Crude rate and relative risk of KR due to primary OA in 153,795 Norwegian men

From: Risk factors for knee replacement due to primary osteoarthritis, a population based, prospective cohort study of 315,495 individuals

  No. of participants Person-years No. of knee replacements KRs per 10,000 person-years (crude rate) Multivariate adjusted RR* (95% CI)
Body Mass Index, kg/m 2  
<23.3 38,967 470,734 32 0.7 1
23.4-25.1 38,099 460,094 79 1.7 2.35 (1.55-3.54)
25.2-27.2 38,918 469,847 93 2.0 2.58 (1.73-3.87)
> = 27.3 37,807 455,912 226 5.0 6.16 (4.23-8.95)
P (test for trend)      <0.0001
Physical activity at work  
Sedentary 58,430 705,549 114 1.6 1
Moderate 43,757 528,129 132 2.5 1.51 (1.18-1.95)
Intermediate 32,304 389,973 90 2.3 1.64 (1.24-2.17)
Intensive 19,118 230,737 94 4.1 2.41 (1.83-3.18)
P (test for trend)      <0.0001
Physical activity at leisure  
Sedentary 29,620 357,537 80 2.2 1
Moderate 80,762 974,895 245 2.5 1.02 (0.79-1.31)
Intermediate 38,982 470,681 98 2.1 0.96 (0.71-1.30)
Intensive 4,350 52,544 6 1.1 0.84 (0.36-1.94)
P (test for trend)      0.668
Height  
< 174 44,106 532,390 126 2.4 1
175-178 36,438 439,896 111 2.5 1.38 (1.06-1.78)
179-182 35,289 426,040 91 2.1 1.33 (1.01-1.76)
> = 183 37,960 458,286 102 2.2 1.64 (1.25-2.15)
P (test for trend)      0.001
Smoking  
Never smoker 46,945 566,770 126 2.2 1
Former smoker 41,371 499,259 161 3.2 1.00 (0.79-1.27)
Smoker 65,479 790,606 143 1.8 0.82 (0.64-1.04)
P (test for trend)      0.092
  1. *Adjusted for age at screening, height, smoking habits, BMI and physical activity at work, and at leisure time.