Table 4 Test characteristics of multiple algorithms among patients aged ≥ 65 y
Algorithms [Pretest prevalence: 1.8%] | TP | TN | FN | FP | Post-test prev.# | Sensitivity [95 CI%] | Specificity [95 CI%] | PPV [95 CI%] | NPV [95 CI%] |
|---|---|---|---|---|---|---|---|---|---|
1 P AND ≥1 Rx ever | 53 | 3248 | 10 | 115 | 4.9% | 84 (75–93) | 97 (96–97) | 32 (25–39) | 100 (100–100) |
2 P AND ≥1 Rx ever | 51 | 3318 | 12 | 45 | 2.8% | 81 (71–91) | 99 (98–99) | 53 (43–63) | 100 (99–100) |
2 P ≥ 60 days apart AND ≥1 RX ever | 49 | 3320 | 14 | 43 | 2.7% | 78 (68–88) | 99 (98–99) | 53 (43–64) | 100 (99–100) |
(1 H ever) OR (2 P AND ≥1 Rx in 1 YR) | 52 | 3337 | 11 | 26 | 2.3% | 83 (73–92) | 99 (99–100) | 67 (56–77) | 100 (100–100) |
(1 H ever) OR (2 P AND ≥1 Rx in 2 YR) | 52 | 3335 | 11 | 28 | 2.3% | 83 (73–92) | 99 (99–100) | 65 (55–76) | 100 (100–100) |
(1 H ever) OR (2 P AND ≥1 RX in 3 YR) | 52 | 3332 | 11 | 31 | 2.4% | 83 (73–92) | 99 (99–99) | 63 (52–73) | 100 (100–100) |
(1 H ever) OR (2 P with ≥ 1 P by specialist AND ≥1 Rx in 1 YR) | 52 | 3347 | 11 | 16 | 2.0% | 83 (73–92) | 100 (99–100) | 77 (66–87) | 100 (100–100) |
(1 H ever) OR (2 P with ≥ 1 P by specialist AND ≥1 Rx in 2 YR) | 52 | 3346 | 11 | 17 | 2.0% | 83 (73–92) | 100 (99–100) | 75 (65–86) | 100 (100–100) |
(1 H ever) OR (2 P with ≥ 1 P by specialist AND ≥ 1 Rx in 3 YR) | 52 | 3345 | 11 | 18 | 2.0% | 83 (73–92) | 100 (99–100) | 74 (64–85) | 100 (100–100) |
(1 H ever) OR (3 P AND ≥ 1 Rx in 1 YR) | 47 | 3346 | 16 | 17 | 1.9% | 75 (64–85) | 100 (99–100) | 73 (63–84) | 100 (99–100) |
(1 H ever) OR (3 P AND ≥ 1 Rx in 2 YR) | 48 | 3342 | 15 | 21 | 2.0% | 76 (66–87) | 99 (99–100) | 70 (59–80) | 100 (99–100) |
(1 H ever) OR (3 P AND ≥ 1 Rx in 3 YR) | 48 | 3342 | 15 | 21 | 2.0% | 76 (66–87) | 99 (99–100) | 70 (59–80) | 100 (99–100) |
(1 H ever) OR (3 P with ≥ 1 P by specialist AND ≥ 1 Rx in 1 YR) | 47 | 3351 | 16 | 12 | 1.7% | 75 (64–85) | 100 (99–100) | 80 (69–90) | 100 (99–100) |
(1 H ever) OR (3 P with ≥ 1 P by specialist AND ≥ 1 Rx in 2 YR) | 48 | 3349 | 15 | 14 | 1.8% | 76 (66–87) | 100 (99–100) | 77 (67–88) | 100 (99–100) |
(1 H ever) OR (3 P with ≥ 1 P by specialist AND ≥ 1 Rx in 3 YR) | 48 | 3348 | 15 | 15 | 1.8% | 76 (66–87) | 100 (99–100) | 76 (66–87) | 100 (99–100) |