Table 3 Test characteristics of multiple algorithms among patients ≥ 20 y
Algorithms [Pretest prevalence: 0.9%] | TP | TN | FN | FP | Post-test prev.# | Sensitivity [95 CI%] | Specificity [95 CI%] | PPV [95 CI%] | NPV [95 CI%] |
|---|---|---|---|---|---|---|---|---|---|
1 H ever | 15 | 7429 | 54 | 2 | 0.2% | 22 (12–32) | 100 (100–100) | 88 (73–100) | 99 (99–100) |
1 H ever OR 1 ER ever | 16 | 7427 | 53 | 4 | 0.3% | 23 (13–33) | 100 (100–100) | 80 (63–98) | 99 (99–100) |
1 P ever | 62 | 7188 | 7 | 243 | 4.1% | 90 (83–97) | 97 (96–97) | 20 (16–25) | 100 (100–100) |
1 P ever by a specialist | 56 | 7377 | 13 | 54 | 1.5% | 81 (72–90) | 99 (99–100) | 51 (42–60) | 100 (100–100) |
2 P by any physician in 1 YR | 58 | 7363 | 11 | 68 | 1.7% | 84 (75–93) | 99 (99–99) | 46 (37–55) | 100 (100–100) |
2 P by any physician in 2 YR | 58 | 7359 | 11 | 72 | 1.7% | 84 (75–93) | 99 (99–99) | 45 (36–53) | 100 (100–100) |
2 P by any physician in 3 YR | 58 | 7352 | 11 | 79 | 1.8% | 84 (75–93) | 99 (99–99) | 42 (34–51) | 100 (100–100) |
3 P by any physician in 1 YR | 55 | 7398 | 14 | 33 | 1.2% | 80 (70–89) | 100 (99–100) | 63 (52–73) | 100 (100–100) |
3 P by any physician in 2 YR | 55 | 7395 | 14 | 54 | 1.2% | 80 (70–89) | 100 (99–100) | 60 (50–71) | 100 (100–100) |
3 P by any physician in 3 YR | 55 | 7393 | 14 | 38 | 1.2% | 80 (70–89) | 100 (99–100) | 59 (49–69) | 100 (100–100) |
2 P with ≥ 1 P by a specialist in 1 YR | 54 | 7404 | 15 | 27 | 1.1% | 78 (69–88) | 100 (100–100) | 67 (56–77) | 100 (100–100) |
2 P with ≥ 1 P by a specialist in 2 YR | 54 | 7404 | 15 | 27 | 1.1% | 78 (69–88) | 100 (100–100) | 67 (56–77) | 100 (100–100) |
2 P with ≥ 1 P by a specialist in 3 YR | 54 | 7401 | 15 | 30 | 1.1% | 78 (69–88) | 100 (100–100) | 64 (54–75) | 100 (100–100) |
3 P with ≥ 1 P by a specialist in 1 YR | 53 | 7419 | 16 | 12 | 0.9% | 77 (67–87) | 100 (100–100) | 82 (72–91) | 100 (100–100) |
3 P with ≥ 1 P by a specialist in 2 YR | 53 | 7418 | 16 | 13 | 0.9% | 77 (67–87) | 100 (100–100) | 80 (71–90) | 100 (100–100) |
3 P with ≥ 1 P by a specialist in 3 YR | 53 | 7418 | 16 | 13 | 0.9% | 77 (67–87) | 100 (100–100) | 80 (71–90) | 100 (100–100) |
(1 H ever) OR (2 P with ≥ 1 P by a specialist in 1 YR) | 55 | 7403 | 14 | 28 | 1.1% | 80 (70–89) | 100 (100–100) | 66 (56–76) | 100 (100–100) |
(1 H ever) OR (2 P with ≥ 1 P by a specialist in 2 YR) | 55 | 7403 | 14 | 28 | 1.1% | 80 (70–89) | 100 (100–100) | 66 (56–76) | 100 (100–100) |
(1 H ever) OR (2 P with ≥ 1 P by a specialist in 3 YR) | 55 | 7400 | 14 | 31 | 1.1% | 80 (70–89) | 100 (99–100) | 64 (54–74) | 100 (100–100) |
(1 H ever) OR (3 P with ≥1 P by a specialist in 1 YR) | 54 | 7417 | 15 | 14 | 0.9% | 78 (69–88) | 100 (100–100) | 79 (70–89) | 100 (100–100) |
(1 H ever) OR (3 P with ≥1 P by a specialist in 2 YR) | 54 | 7416 | 15 | 15 | 0.9% | 78 (69–88) | 100 (100–100) | 78 (69–88) | 100 (100–100) |
(1 H ever) OR (3 P with ≥1 P by a specialist in 3 YR) | 54 | 7416 | 15 | 15 | 0.9% | 78 (69–88) | 100 (100–100) | 78 (69–88) | 100 (100–100) |
(1 H ever) OR (2 P ≥ 8 weeks apart in 2 YR, no exclusions* | 57 | 7378 | 12 | 53 | 1.5% | 83 (74–92) | 99 (99–100) | 52 (43–61) | 100 (100–100) |
(1 H ever) OR (2 P ≥ 8 weeks apart in 2 YR) excluding Case A or Case B | 41 | 7401 | 28 | 30 | 0.9% | 59 (48–71) | 100 (100–100) | 58 (46–69) | 100 (100–100) |
(1 H ever) OR (2 P ≥ 8 weeks apart in 3 YR) excluding Case A or Case B | 41 | 7396 | 28 | 35 | 1.0% | 59 (48–71) | 100 (99–100) | 54 (43–65) | 100 (100–100) |
(1 H ever) OR (2 P ≥ 8 weeks apart in 4 YR) excluding Case A or Case B | 43 | 7394 | 26 | 37 | 1.1% | 62 (51–74) | 100 (99–100) | 54 (43–65) | 100 (100–100) |
(1 H ever) OR (2 P ≥ 8 weeks apart in 5 YR) excluding Case A or Case B | 44 | 7390 | 25 | 41 | 1.1% | 64 (52–75) | 99 (99–100) | 52 (41–62) | 100 (100–100) |
(1 H ever) OR (2 P ≥ 8 weeks apart in 2 YR) excluding Case A | 41 | 7402 | 28 | 29 | 0.9% | 59 (48–71) | 100 (100–100) | 59 (47–70) | 100 (100–100) |