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Table 1 Demographic and desease characteristics of the patients included in NinJa database

From: Clinical characteristics of rheumatoid arthritis patients undergoing cervical spine surgery: an analysis of National Database of Rheumatic Diseases in Japan

Fiscal year 2003 2004 2005 2006 2007 2008 2009 2010 2011 p-value Coefficient
Total number of registered patients 4100 3994 4650 5152 5463 6502 7179 7254 10368   
Age (years) (IQR) 62(55–69) 63(55–70) 64(56–71) 63(56–71) 64(56–71) 64(56–71) 64(56–72) 65(57–72) 65(56–72) <0.0001  
Gender (female:male) 3410:700 3313:681 3832:818 4229:923 4448:1015 5346:1156 5895:1284 5921:1333 8375:1993 0.7341  
Disease dutaion (years) (IQR) 11(5–20) 11(5–19) 10(5–19) 10(5–19) 9(4–19) 10(5–19) 10(5–19) 10(5–19) 9(4–18) 0.0020  
Use of MTX (%) 36 48 53 53 47 51 64 58 60 0.0084 2.43
Use of corticosteroid (%) 64 63 62 63 61 58 53 53 49 0.0002 -1.88
Use of biologics (%) 0.4 2.1 4.3 9 12 14 20 19 20 <0.0001 2.76
Cervical spine surgery (cases) (%) 8 (0.19) 7 (0.17) 4 (0.08) 6 (0.12) 8 (0.15) 10 (0.15) 10 (0.14) 15 (0.21) 30 (0.29) 0.1593 0.01
Total knee replacement (cases) (%) 146 (3.55) 121 (3.02) 117 (2.52) 130 (2.52) 132 (2.42) 118 (1.81) 156 (2.17) 133 (1.87) 158 (1.52) 0.0002 -0.21
Total hip replacement (cases) (%) 33 (0.80) 37 (0.93) 50 (1.08) 48 (0.93) 45 (0.82) 51 (0.78) 46 (0.64) 43 (0.59) 56 (0.54) 0.0098 -0.05
  1. The data are represented as the medians (IQR). The yearly differences were analyzed by the Tukey-Kramer method.
  2. Yearly trends were analyzed by a single regression model, and are expressed by coefficients and p-values.