Table 3 Variables associated with risk of incident non-traumatic fracture over 10 years (multivariate analysis)

Diabetes status

No diabetes

reference

Non-insulin-dependent diabetes mellitus

1.02

0.77-1.35

0.864

Insulin-dependent diabetes mellitus

2.50

1.60-3.90

<0.001

Gender

Male

reference

Female

1.54

1.30-1.82

<0.001

Age (years)

50-59

reference

60-69

0.95

0.80-1.13

0.551

70-79

1.40

1.17-1.67

<0.001

≥ 80

1.69

1.30-2.19

<0.001

Body mass index

18.5 ≤ BMI <25

reference

BMI < 18.5

0.82

0.50-1.37

0.451

25 ≤ BMI <30

1.09

0.94-1.26

0.235

30 ≤ BMI < 35

1.28

1.06-1.54

0.011

BMI ≥ 35

1.35

1.02-1.80

0.037

Femoral neck BMD T-score (per SD increase)

0.69

0.64-0.76

<0.001

BMD ≥ -1.0

reference

-2.5 < BMD < -1.0

1.59

1.35-1.88

<0.001

BMD ≤ -2.5

2.56

2.04-3.21

<0.001

Previous history of fracture

No

reference

Yes

1.58

1.39-1.79

<0.001

Corticosteroid use ^*

No

reference

Yes

1.35

1.07-1.69

0.010

Bisphosphonate use (ever use over the 10 year study)

No

reference

Yes

1.56

1.36-1.79

<0.001