|
Sensitivity analysis
|
n (%)
|
Age-adjusted models
|
Fully-adjusted models
|
|---|
|
OR (95% CI)a
|
P-value
|
AUCb
|
OR (95% CI)
|
P-value
|
AUC
|
|---|
|
Any falls at baseline and during the 3-year follow-up
c
|
|
Baseline falls
|
1483 (37.51)
|
1.03 (1.03-1.04)
|
<0.001
|
0.61
|
1.04 (1.03-1.04)
|
<0.001
|
0.62
|
|
Women < 65 years
|
540 (39.16)
|
1.04 (1.03-1.05)
|
<0.001
|
0.64
|
1.04 (1.03-1.05)
|
<0.001
|
0.64
|
|
Women ≥ 65 years
|
943 (36.62)
|
1.03 (1.02-1.04)
|
<0.001
|
0.61
|
1.03 (1.03-1.04)
|
<0.001
|
0.62
|
|
New incident falls
d
|
1204 (51.43)
|
1.02 (1.02-1.03)
|
<0.001
|
0.59
|
1.02 (1.02-1.03)
|
<0.001
|
0.60
|
|
Women < 65 years
|
384 (47.64)
|
1.02 (1.00-1.03)
|
0.015
|
0.56
|
1.02 (1.00-1.03)
|
0.018
|
0.58
|
|
Women ≥ 65 years
|
820 (53.42)
|
1.02 (1.02-1.03)
|
<0.001
|
0.61
|
1.03 (1.02-1.04)
|
<0.001
|
0.61
|
|
Recurrence of falls
e
|
1135 (81.54)
|
1.04 (1.03-1.05)
|
<0.001
|
0.64
|
1.04 (1.03-1.06)
|
<0.001
|
0.64
|
|
Women < 65 years
|
419 (80.58)
|
1.05 (1.03-1.07)
|
<0.001
|
0.66
|
1.06 (1.03-1.08)
|
<0.001
|
0.68
|
|
Women ≥ 65 years
|
716 (82.11)
|
1.04 (1.02-1.05)
|
<0.001
|
0.63
|
1.04 (1.02-1.05)
|
<0.001
|
0.66
|
|
Analysis with multiple imputation for missing data
f
|
1317 (33.05)g
|
1.03 (1.03-1.04)
|
<0.001
|
0.61
|
1.02 (1.02-1.03)
|
<0.001
|
0.69
|
|
Women < 65 years
|
448 (32.35)g
|
1.03 (1.02-1.04)
|
<0.001
|
0.60
|
1.02 (1.01-1.03)
|
0.004
|
0.72
|
|
Women ≥ 65 years
|
869 (33.42)g
|
1.03 (1.03-1.04)
|
<0.001
|
0.62
|
1.02 (1.02-1.03)
|
<0.001
|
0.68
|
-
aOR: odds ratio; CI: confidence interval; All statistics measured a change of 0.01 on the frailty index.
-
bAUC: areas under the receiver operating characteristic curves.
-
cAnalyses adjusted for age, BMI, smoking, drinking, and education.
-
dDefined as women had any falls during the follow-up but without baseline falls.
-
eDefined as women had any falls during the follow-up and with baseline falls.
-
fFor any falls during the third year of follow-up; Analyses adjusted for age, BMI, smoking, drinking, education, and baseline falls.
-
gNumbers obtained after 10 multiple imputation.
