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Table 2 Frequency and severity of low immunoglobulin levels

From: The effect of rituximab therapy on immunoglobulin levels in patients with multisystem autoimmune disease

  IgG IgM <0.4 g/L IgA <0.8 g/L
< 6 g/L Mild Moderate Severe
5-5.9 g/L 3-4.9 g/L < 3 g/L
Baseline hypogammaglobulinaemia 18 (13%) 6 (5%) 9 (6%) 3 (2%) 14 (10%) 14 (10%)
Hypogammaglobulinaemia 61 (34%) 18 (10%) 36 (20%) 7 (4%) 90 (51%) 40 (23%)
  1. Baseline hypogammaglobulinaemia (N = 136): total number and proportion in parentheses of patients with low immunoglobulin levels at time of first rituximab.
  2. Hypogammaglobulinaemia (N = 177): total number and proportion in parentheses of patients with low immunoglobulin levels following rituximab for at least three consecutive months at some point during follow-up.