Skip to main content

Table 4 Events during or within 24 hours of each rituximab infusion

From: Safety of infusing rituximab at a more rapid rate in patients with rheumatoid arthritis: results from the RATE-RA study

Events Infusion 1 (N = 351) n (%)(95% CI)a Infusion 2 (N = 337) n (%)(95% CI)a Infusion 3 (N = 289) n (%)(95% CI)a Infusion 4 (N = 278) n (%)(95% CI)a
Serious IRRs 0 (0) (- to 0.8) 0 (0) (- to 0.9) 0 (0) (- to 1.0) 0 (0) (- to 1.1)
IRRs and other AEs 62 (17.7) (13.8 to 22.1) 24 (7.1) (4.6 to 10.4) 22 (7.6) (4.8 to 11.3) 5 (1.8) (0.6 to 4.1)
Serious AEs 0 (0) (- to 0.8) 0 (0) (- to 0.9) 0 (0) (- to 1.0) 0 (0) (- to 1.1)
CTC grade 3/4 AEs 2 (0.6) (0.1 to 2.0) 2 (0.6) (0.1 to 2.0) 0 (0) (0.1 to 2.1) 0 (0) (0.0 to 1.3)
Infusion stopped/slowed/interruptedb 43 (12.3) (9.0 to 16.1) 13 (3.9) (2.1 to 6.5) 19 (6.6) (4.0 to 10.1) 3 (1.1) (0.2 to 3.1)
  1. AE, adverse event; CTC, Common Terminology Criteria; IRRs, infusion-related reactions. aOne-sided CI for serious events. bDue to AE, medication error, or other reason such as bathroom break.