Skip to main content

Table 1 Infusion schedule

From: Safety of infusing rituximab at a more rapid rate in patients with rheumatoid arthritis: results from the RATE-RA study

Time (min) Infusion rate Dose in 30 minutes Cumulative dose
  (mg/h) (mL/h) (mg) (mg)
Infusion 1
0-30 50 12.5 25 25
31-60 100 25 50 75
61-90 150 37.5 75 150
91-120 200 50 100 250
121-150 250 62.5 125 375
151-180 300 75 150 525
181-210 350 87.5 175 700
211-240 400 100 200 900
241-255 400 100 200 1000
Infusion 2, 3 and 4
0-30 250 62.5 125 125
31-60 600 150 300 425
61-90 600 150 300 725
91 ≈ 120 600 150 275 1000
  1. The total estimated time to complete a 1000-mg dose at Infusion 1 is 4 hours, 15 minutes (4.25 hours) with 8 infusion rate changes. The total estimated time to complete a 1000-mg dose (1000 mg diluted in 250 mL of normal saline or D5W) at Infusion 2, 3 and 4 is approximately 2 hours with 1 infusion rate change.