Skip to main content

Table 2 Univariate associations between CV risk variables and prospective CV events in GA and non-GA patients

From: Hyperuricaemia: a marker of increased cardiovascular risk in rheumatic patients: analysis of the ACT-CVD cohort

  GA (172) Non-GA(686)
  Event-free (154) Event (18) p (event vs. none) Event-free (640) Event (46) p (event vs. none)
Tertiles serum uric acid (% 1st/2nd/3rd) 37.3/32.0/30.7 33.3/16.7/50.0 0.208 40.6/28.3/31.2 15.9/25.0/59.1 0.000*
Uric acid lowering therapy, % 74.0 66.7 0.504 0 0 n.a.
Allopurinol, % 64.3 66.7 0.842 0 0 n.a.
Sex, % male 91.6 72.2 0.011* 24.8 37.0 0.069*
Age, mean, years 58.5 68.8 0.000* 58.6 64.9 0.001*
Systolic blood pressure, mean, mmHg 152.0 143.0 0.092* 143.9 152.1 0.015*
Antihypertensive therapy, % 34.4 77.8 0.000* 26.3 45.7 0.004*
Smoking, % 26.0 11.1 0.147* 22.0 23.9 0.767
TC/HDL ratio, mean 4.83 4.71 0.623 3.74 3.95 0.265
Total cholesterol, mean 5.38 4.83 0.037* 5.38 5.19 0.234
HDL cholesterol, mean 1.18 1.05 0.104* 1.53 1.40 0.057*
Statin therapy, % 11.7 22.2 0.205 8.0 15.2 0.088*
Diabetes, % 5.8 11.1 0.387 6.4 6.5 0.975
GlyHb, mean, %Hb 5.83 6.58 0.004* 5.83 5.91 0.408
BMI, mean, kg/m2 30.1 32.9 0.017* 27.4 28.8 0.058*
MDRD, mean, ml/min 83.5 58.1 0.002* 89.7 83.2 0.091*
NT proBNP, mean, nmol/L 14.5 230.9 0.083* 14.1 45.4 0.005*
hsCRP, mean, g/l 5.76 9.44 0.238 5.90 7.21 0.390
Corticosteroids, % 0.0 0.0 - 10.0 10.9 0.850
  1. GA: gouty arthritis; hsCRP: high sensitivity C-reactive protein; TC: Total cholesterol; HDL: high density lipoprotein; GlyHb: glycated haemoglobin; BMI: body mass index; MDRD: modification of diet in renal disease; NT proBNP: N-terminal pro-brain natriuretic peptide. *variable included in the respective COX regression analyses.