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Table 3 Association analyses for FN-1 SNPs with OA in the combined analyses of both study groups

From: An intron polymorphism of the fibronectin gene is associated with end-stage knee osteoarthritis in a Han Chinese population: two independent case- control studies

SNP   Case Control Simply pooled OR (95% CI)# p ORMeta(95% CI)# I2
rs10202709 GG 864 651 1   1  
  GA 61 40 1.13 (0.74-1.72) 0.583 1.15 (0.63-2.10) 47.99
  AA 3 2 1.15 (0.19-711) 0.881 1.13 (0.18-7.09) 0
  G 0.96 0.97 1   1  
  A 0.04 0.03 1.24 (0.76-1.67) 0.565 1.16 (0.72-1.87) 23.50
rs6725958 CC 233 213 1   1  
  CA 489 355 1.17 (0.92-1.48) 0.201 1.08 (0.76-1.53) 0
  AA 206 125 1.39 (1.03-1.88) 0.030 1.40 (1.04-1.89) 0
  C 0.52 0.56 1   1  
  A 0.48 0.44 1.17 (1.01-1.35) 0.033 1.17 (1.01-1.35) 0
rs940739 AA 550 468 1   1  
  AT 337 198 1.44 (1.16-1.80) 0.001& 1.46 (1.17-1.83) 0
  TT 41 27 1.14 (0.68-1.91) 0.624 1.11 (0.67-1.86) 0
  A 0.77 0.82 1   1  
  T 0.23 0.18 1.28 (1.07-1.53) 0.008 1.28 (1.07-1.54) 0
rs2304573 GG 529 385 1   1  
  GA 335 256 0.97 (0.78-1.20) 0.754 0.97 (0.78-1.21) 0
  AA 64 52 0.93 (0.62-1.38) 0.701 0.94 (0.63-1.40) 0
  G 0.75 0.74 1   1  
  A 0.25 0.26 0.96 (0.82-1.13) 0.647 0.97 (0.82-1.14) 0
rs11651 AA 441 305 1   1  
  AG 383 294 0.90 (0.73-1.12) 0.359 0.91 (0.73-1.13) 0
  GG 104 94 0.78 (0.57-1.08) 0.138 0.78 (0.57-1.08) 0
  A 0.68 0.65 1   1  
  G 0.32 0.35 0.88 (0.76-1.03) 0.112 0.89 (0.76-1.04) 0
rs3796123 TT 768 577 1   1  
  TA 148 112 0.95 (0.72-1.25) 0.691 0.96 (0.73-1.27) 0
  AA 12 4 2.14 (0.67-6.87) 0.202 2.14 (0.38-12.14) 44.49
  T 0.91 0.91 1   1  
  A 0.09 0.09 1.03 (0.80-1.33) 0.818 1.04 (0.75-1.44) 36.03
  1. #Data have been adjusted by gender, age and BMI; &p-values were based upon Bonferroni’s method.