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Table 2 Genotype distributions of FN-1 polymorphisms and their association with OA risk

From: An intron polymorphism of the fibronectin gene is associated with end-stage knee osteoarthritis in a Han Chinese population: two independent case- control studies

SNP   Study 1   Study 2  
Case Control Adjusted OR (95% CI)# Case Control Adjusted OR (95% CI)#
rs10202709 GG 376 300 1 488 351 1
  GA 26 13 1.64 (0.81-3.33) 35 27 0.88 (0.52-1.52)
  AA 1 1 1.00 (0.06-16.72) 2 1 1.24 (0.11-14.25)
  G 0.96 0.98 1 0.96 0.96 1
  A 0.04 0.02 1.54 (0.80-2.97) 0.04 0.04 0.94 (0.55-1.52)
rs6725958 CC 113 102 1 120 111 1
  CA 200 158 1.08 (0.76-1.54) 289 197 1.25 (0.90-1.72)
  AA 90 54 1.44 (0.92-2.25) 116 71 1.37 (0.92-2.05)
  C 0.53 0.58 1 0.50 0.55 1
  A 0.47 0.42 1.18 (0.95-1.47) 0.50 0.45 1.16 (0.96-1.41)
rs940739 AA 240 208 1 310 260 1
  AT 146 94 1.44 (1.03-2.01)* 191 104 1.48 (1.10-1.99)*
  TT 17 12 1.07 (0.49-2.36) 24 15 1.15 (0.58-2.28)
  A 0.78 0.81 1 0.77 0.82 1
  T 0.22 0.19 1.26 (0.96-1.65) 0.23 0.18 1.30 (1.02-1.65)*
rs2304573 GG 227 173 1 302 212 1
  GA 146 119 0.95 (0.68-1.31) 189 137 0.99 (0.74-1.33)
  AA 30 22 1.15 (0.63-2.10) 34 30 0.80 (0.47-1.36)
  G 0.74 0.74 1 0.75 0.74 1
  A 0.26 0.26 1.02 (0.79-1.30) 0.25 0.26 0.93 (0.75-1.17)
rs11651 AA 190 138 1 251 167 1
  AG 170 130 0.93 (0.67-1.29) 213 164 0.89 (0.66-1.19)
  GG 43 46 0.71 (0.44-1.16) 61 48 0.85 (0.55-1.31)
  A 0.68 0.65 1 0.68 0.66 1
  G 0.32 0.35 0.86 (0.68-1.08) 0.32 0.34 0.91 (0.74-1.11)
rs3796123 TT 338 259 1 430 318 1
  TA 61 52 0.83 (0.54-1.27) 87 60 1.07 (0.74-1.54)
  AA 4 3 1.02 (0.22-4.68) 8 1 6.17 (0.73-52.51)
  T 0.91 0.91 1 0.90 0.92 1
  A 0.09 0.09 0.87 (0.59-1.27) 0.10 0.08 1.21 (0.86-1.70)
  1. * p < 0.05; #Data have been adjusted by gender, age and BMI.