Figure 3From: Regulation of ubiquitin-proteasome and autophagy pathways after acute LPS and epoxomicin administration in mice Phosphorylation state of UPP regulatory proteins. Phosphorylation state of AktSer473 (A), protein level of Akt (B), phosphorylation states FoxO3aThr32 (C) and 4E-BP1Thr37/46 (D) in the GAS of mice 8 hours after administration of LPS 7.5 mg/kg with or without epoxomicin 0.5 mg/kg treatment. Values are means ± SEM. ** p < 0.01, *** p < 0.001 compared with control (C). §: Western blot analyses for 4E-BP1 Thr37/46 and FoxO3aThr32 originate from the same gel and the representative western blot comes from the same set of samples. Therefore, loading control eEF2 is the same.Back to article page