Transcriptional regulation of UPP. mRNA expression levels of MuRF1 (A), MAFbx (B), Psmb1 (C) and Psmc2 (D) in the GAS of mice 8 hours after administration of LPS 7.5 mg/kg with or without epoxomicin 0.5 mg/kg treatment (L + E and L, respectively). Values are means ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001 compared with control (C); #
p < 0.05 compared with LPS (L).