Table 1 Parameter estimates for predictors in the final linear mixed-effects regression model, with SHC during the study time span ^† as outcome ( n = 23)

Estimates of fixed effects

Female *G carrier (male *G)

6.59

2.37

1.2, 11.37

0.008

Pain score (0-10)^†

0.92

0.39

0.12, 1.72

0.025

Pain duration (weeks)

0.14

0.05

0.04, 0.25

0.010

Time 1 year (baseline)

1.91

1.13

-0.42, 4.24

0.103

Estimates of covariance parameters

Residual

9.19

3.04

4.80, 17.59

0.003

Random effects

1.75

0.65

0.85, 3.63

0.007