Table 1 Preclinical study characteristics and results
Study | Animal model | Stem cell therapy | Results | |||||
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Histology | Imaging | ||||
| Â | Â | Â | Bone formation | Angiogenesis | X-ray | SPECT | CT | MR |
Wen et al. [30] | Rabbit | BMMNC-MSC | +ve | +ve* | -- | -- | +ve | +ve |
Sun et al. [6] | Rabbit | BMMNC | +ve* | +ve* | -- | -- | +ve* | -- |
Yan et al. [12] | Dog | BMMNC-MSC | +ve* | -- | -- | -- | -- | -- |
Feitosa et al. [4] | Sheep | hIDPSC, BMMNC-MSC | +ve | -- | -- | -- | -- | -- |
Abudusaimi et al. [10] | Rabbit | ADSC | +ve | -- | -- | -- | +ve* | -- |
Aimaiti et al. [34] | Rabbit | ADSC | +ve | +ve | -- | -- | +ve* | -- |
Song et al. [17] | Rabbit | PBSC | +ve | +ve* | -- | -- | -- | -- |
Sun et al. [31] | Rabbit | EPC | +ve* | +ve* | -- | -- | -- | -- |
Hang et al. [11] | Dog | BMMNC-MSC | +ve* | +ve* | +ve | +ve | -- | -- |
Wen et al. [33] | Rabbit | BMMNC-MSC | +ve | -- | -- | -- | -- | -- |
Xie et al. [32] | Rabbit | cBMMNC | +ve* | +ve* | -- | -- | +ve* | -- |