Skip to main content

Table 3 Characteristics of the 6 studies included in the literature review

From: Cardiovascular case fatality in rheumatoid arthritis is decreasing; first prospective analysis of a current low disease activity rheumatoid arthritis cohort and review of the literature

Reference Country Enrolment period Mean follow up (years) Sample type Inception cohort RA definition % female Mean age at entry Previous CVD excluded CVD included Outcome ascertainment N Person-years at risk CV events (n) CV events/ 1000 person-years Fatal CV events (%)
Del Rincon, 2001 [13] USA 1996 0.9 Clinic based No ACR 1987 62.3 56* Yes MI, CVA, CV death Medical record 236 204 7 34.3 28.6
Assous, 2007 [23] France 1998-1999 5.4 Clinic based No ACR 1987 83.8 55 Yes MI, CVA, CV death Medical record 239 NAV 17 13 52.9
Solomon, 2006 [23] USA 1999-2003 2.8 Population based No ICD code 71.1 NAV No MI, CVA, CV death ICD code 25,385 70,612 1,042 14.8 41.2
Peters, 2009 [24] Netherlands 2001-2002 2.7 Clinic based No ACR 1987 65 63 Yes Coronary disease, CVA, CV and sudden death Medical record 272 729 19 26.1 12.9**
Meek, 2013*** [19] Netherlands 2009-2011 2.9 Clinic based No Clinical diagnosis 72.3 59 Yes Coronary disease, CVA, CV and sudden death Medical record 480 1380 29 21 6.9
Maradit-Kremers, 2005 [9] USA 1955-1995 14.7 Population based Yes ACR 1987 73 58 Yes MI, CABG, PTCA, AP, CV and sudden death Medical record 603 8,672 109 13.0 23.8
Holmqvist, 2010 [25] Sweden 1995-2006 4.1 Population based Yes ACR 1987 71.0 56.9 Yes MI, AP, CABG, PTCA, CV death Hospital discharge register 7,469 33,436 341 10.2 11.1
  1. Studies are placed in order of cohort type (non-inception vs inception) and enrolment period. RA: rheumatoid arthritis; CVD: cardiovascular disease; MI: myocardial infarction; CVA: cerebrovascular incident; CV: cardiovascular; CABG: coronary artery bypass graft; PTCA: percutaneous transluminal coronary angioplasty; AP: angina pectoris; NAV: not available. * Median. ** non-published data received from the authors. ***data from the ACT-CVD cohort presented in htis article.