Depression in primary TKA and higher medical comorbidities in revision TKA are associated with suboptimal subjective improvement in knee function

Table 5 Univariate association of comorbidity with overall knee status at 2- and 5-years after Revision TKA

		2-year			5-year
Variable	Overall knee status category^a	Overall knee status n/N (%)	Odds ratio (95% CI)	p-value	Overall knee status n/N (%)	Odds ratio (95%) CI)	p-value
Deyo-Charlson index^b	Better	Not applicable	1.4 (0.8, 2.4)	0.24	Not applicable	0.5 (0.2, 1.1)	0.08
Deyo-Charlson index^b	Much better	Not applicable	1.2 (0.7, 1.9)	0.50	Not applicable	0.6 (0.3, 1.2)	0.13
Anxiety: No	Better	241/1,257 = 19.2%	1.0		151/727 = 20.8%	1.0
Yes	Better	18/58 = 31.0%	1.6 (0.7, 3.6)	0.28	8/18 = 44.4%	2.0 (0.5, 7.6)	0.33
Anxiety: No	Much better	827/1,257 = 65.8%	1.0		465/727 = 64.0%	1.0
Yes	Much better	31/58 = 53.4%	0.8 (0.4, 1.7)	0.54	7/18 = 38.9%	0.6 (0.1, 2.2)	0.40
Depression: No	Better	231/1,212 = 19.1%		1.0	147/707 = 20.8%	1.0
Yes	Better	28/103 = 27.2%	1.1 (0.6, 2.1)	0.67	12/38 = 31.6%	1.0 (0.4, 2.3)	0.91
Depression: No	Much better	802/1,212 = 66.2%			455/707 = 64.4%	1.0
Yes	Much better	56/103 = 54.4%	0.7 (0.4, 1.1)	0.13	17/38 = 44.7%	0.4 (0.2, 1.0)	0.05

^aReference category for overall knee status was a patient response of same or worse index knee status; ^bper 5-point increase.

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