Depression in primary TKA and higher medical comorbidities in revision TKA are associated with suboptimal subjective improvement in knee function

Table 4 Multivariable-adjusted ^a odds of Overall Knee status at 2- and 5-years following Primary TKA or Revision TKA

	Overall knee status at 2 years		p-value	Overall knee status at 5 years	p-value
	Odds ratio (95% CI)			Odds ratio (95% CI)
Primary TKA
Deyo-Charlson index (5-point increase)
	Better	1.0 (0.6 to 1.7)	0.90	1.0 (0.6 to 1.5)	0.94
	Much better	0.9 (0.6 to 1.3)	0.47	0.8 (0.6 to 1.2)	0.25
Anxiety
	Better	1.3 (0.6 to 2.8)	0.58	0.9 (0.5 to 1.8)	0.83
	Much better	0.9 (0.4 to 1.8)	0.71	0.8 (0.5 to 1.5)	0.50
Depression
	Better	0.6 (0.3 to 1.2)	0.17	1.1 (0.7 to 2.0)	0.61
	Much better	0.5 (0.3 to 0.9)	0.02	0.9 (0.5 to 1.4)	0.55
Revision TKA
Deyo-Charlson index (5-point increase)
	Better	1.5 (0.8 to 2.7)	0.21	0.4 (0.2 to 1.1)	0.07
	Much better	1.2 (0.7 to 2.1)	0.48	0.5 (0.2 to 1.0)	0.05
Anxiety
	Better	1.3 (0.5 to 3.3)	0.60	1.8 (0.4 to 8.0)	0.45
	Much better	0.9 (0.4 to 2.0)	0.75	0.6 (0.1 to 2.9)	0.56
Depression
	Better	1.0 (0.5 to 2.0)	0.98	1.1 (0.4 to 3.2)	0.86
	Much better	0.6 (0.4 to 1.2)	0.17	0.5 (0.2 to 1.4)	0.21

^aMultivariable model additionally adjusted for age to gender to BMI to American Society of Anesthesiologist (ASA) class to distance from medical center to operative diagnosis to implant fixation (cement status) to Deyo-Charlson index to anxiety and depression.

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