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Figure 4 | BMC Musculoskeletal Disorders

Figure 4

From: Inhibitors of endopeptidase and angiotensin-converting enzyme lead to an amplification of the morphological changes and an upregulation of the substance P system in a muscle overuse model

Figure 4

Sections of soleus muscle specimens; C + Th group (A-C) and SP + C + Th group, non-exercised side (D). The sections were stained for SP (antibody sc-14104) (A,C) and NK-1R (B,D). In (A), an arteriole with marked tachykinin-like/(SP-Like) immunoreactions in its wall is seen (middle) and the region shown in (B) conforms to a region with marked infiltration of white blood cells. SP-like/ immunoreactions (A) and NK-1R immunoreactions (B) are seen in white blood cells (arrows). Parts of nerve fascicles are seen in (C) and (D). Immunoreactions are seen in these in both (C) and (D) (arrows). Bars = 25 μm.

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