Table 1 Clinical data of individuals with OI type V
Individual | Age (years) | Sex | Age at first fracture | Number of clinical fractures | Age at which elbow deformity noted | Age at diagnosis of OI | Age at diagnosis of OI type V | Forearm interosseous membrane calcification and radial head dislocation | Hyperplastic callus | Height (Z-score) | Baseline BMD* | Physical activity |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
73.3 | 10 | F | Birth | ~18 | 1 month | Birth | 5 years | Present | Present | −2.37 | TB −2.69, LS −4.87 at 14 months | Walking unaided |
88.3 | 11 | M | Birth | >20 | 4 years | Birth | 4 years | Present | Present | 0.359 | TB −3 at 10 years | Walking unaided |
91.3 | 25 | F | 3 years | ~8 | <1 year | 9 years | 9 years | Present | Absent | −1.171 | TB −2.90, LS −2.73 at 6 years | NA |
150.3 | 61 | M | 6 weeks | >15 | 30 years | 6 weeks | 60 years | Present | Absent | −10.69 | NA | NA |
176.3 | 14 | F | <12 months | ~20 | NA | 13 months | 12 years | Present | Present | −3.94 | NA | Wheelchair to mobilise |
181.3 | 7 | M | <11 months | 20-30 | NA | 13 months | 7 years | Present | Present | −1.07 | LS −7.8 at 13 months | Walking for 45 min |
182.3 | 8 | F | <1 year | ~35 | 4 years | 2 years | 8 years | Present | Present | −3.0 | LS −4.7 at 2 years | Walking for 30 min intervals |
185.3 | 32 | F | Never clinically fractured | 0 | 1 month | 31 years | 31 years | Present | Absent | −2.79 | NA | Walking unaided |
185.4 | 5 | M | 2 years | 3 | 2.5 years | 4 years | 4 years | Present | Absent | −1.10 | NA | Walking unaided |