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Table 7 Studies examining the relationship between poor mental health and knee pain

From: Are depression, anxiety and poor mental health risk factors for knee pain? A systematic review

Author (year)

Study design

Assessment of general mental health

Assessment of pain

Results

Conclusion

Quality score

O’Reilly (1998)

Cross-sectional

SF-36 Questionnaire – Mental Health Component

Knee pain on most days for at least a month (in the past year)

Mental health score (<61): OR: 2.1 95% CI: 1.7-2.6

Lower mental health scores were associated with increased odds of knee pain.

45

Knee pain: Median (IQR): 72(56–84)

No knee pain: Median (IQR): 76(64–88). P < 0.001

Matsudaira (2011)

Cross-sectional

SF36 subscale

Self reported knee pain in past month or in the past year

Knee pain and mental health: Not significant (Data not provided)

There was no association found between knee pain and general mental health.

82

Harcombe (2010)

Cross-sectional

Mental Health Inventory-5 (MHI-5)

Self-reported knee pain lasting for more than a day in the month

Knee pain and mental health: OR (95% CI)= 0.96 (0.90 to 1.02); p value=0.194

There was no association between self-reported knee pain and mental health.

73

Standardised Nordic Questionnaires for MSDs and Brief Symptom Inventory diagram showing the area of the body

Davis (1992)

Cross-sectional

Psychological Wellbeing: NHANES General Wellbeing Index

Pain on most days lasting one month in the past year or knee pain on active or passive motion during the examination

Psychological wellbeing (score ≤70 & reference group >94)

Psychological wellbeing was associated with knee pain among participants with and without radiographic OA.

45

OA and No OA: OR (95% CI)= 1.4 (1.0 to 2.0)

OA ± Pain: OR (95% CI)= 3.7 (1.8 to 7.6)

Pain ± OA: OR (95% CI)= 3.2 (2.1 to 5.0)

  1. NHANES, National Health and Nutritional Examination Survey; PFS, Physical Functioning Score; WOMAC, Western Ontario and McMaster University Osteoarthritis Index; PCI, Pain Coping Inventory; 4DSQ, Four Dimensional Symptom Questionnaire; CES-D, Centre for Epidemiological Studies Depression Scale; QOL, Quality of Life; SF-36, Short-Form-36 Health Survey; SSS, Social Support Scale; VAS, Visual Analogue Scale; OA, osteoarthritis; K/L scale, Kellgren and Lawrence Atlas of Standard Radiographs of Arthritis; WOMAC, Western Ontario and McMaster University Arthritis Index; MPQ, McGill Pain Questionnaire; AIMS, Arthritis Impact Measurement Scales; ACR, American College of Rheumatology; NA, not available; PFS, Physical Functioning Scale; IRGL, Invloed van Reuma op Gezondheid en Leefwijze (Dutch version of the Arthritis Impact Measurement Scale).