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Table 1 Baseline characteristics of the SWEFOT participants for all patients and also within each treatment group

From: Evaluation of hand bone loss by digital X-ray radiogrammetry as a complement to clinical and radiographic assessment in early rheumatoid arthritis: results from the SWEFOT trial

 

All SWEFOT patients (N = 487)

All study patients (N = 159)

MTX responders (N = 49)

Triple therapy (N = 55)

Combination MTX + INF (N = 55)

p-value

Disease duration, months

6.16 (3.20)

6.08 (3.20)

5.86 (3.12)

6.00 (3.10)

6.35 (3.40)

0.79

Sex, female

70.6 (344)

72.3 (115)

63.3 (31)

74.5 (41)

78.2 (43)

0.21

ACPA pos.% (n)

63.7 (310)

60.3 (91)

55.6 (25)

62.3 (33)

62.3 (33)

0.74

RF pos.% (n)

68.4 (333)

69.1 (96)

68.2 (30)

71.4 (35)

67.4 (31)

0.90

DAS 28

5.73 (1.01)

5.70 (1.00)

5.23 (0.99)

5.99 (1.02)

5.85 (0.92)

<0.001*/0.004**/1.0^

ESR (mm)

39.8 (28.1)

38.6 (26.6)

31.2 (24.4)

49.3 (27.7)

34.4 (24.3)

0.001*/1.0**/0.008^

CRP (mg/L)

33.7 (42.4)

35.1 (40.4)

27.3 (40.1)

47.1 (41.2)

29.8 (37.7)

0.04*/1.0**/0.07^

HAQ

1.19 (0.58)

1.19 (0.59)

0.97 (0.47)

1.35 (0.65)

1.25 (0.57)

0.003*/0.04**/1.0^

T-SHS

4.54 (8.01)

4.79 (7.85)

3.04 (6.00)

5.98 (8.53)

5.08 (8.37)

0.07

ES

1.91 (3.75)

1.99 (3.56)

1.71 (2.87)

2.43 (4.32)

1.76 (3.21)

0.52

DXR-BMD (g/cm2)

----

0.58 (0.08)

0.59 (0.08)

0.57 (0.06)

0.56 (0.08)

0.14

  1. The values are mean (SD) or percentages (%).
  2. *Between MTX-responders and triple therapy.
  3. ** Between MTX-responders and combination MTX + INF.
  4. ^ Between triple therapy and combination MTX + INF.
  5. Abbreviation: ACPA: Anti-citrullinated protein antibody, RF: Rheumatoid factor, DAS28: 28 joint-based disease activity score, ESR: Erythrocyte sedimentation rate, CRP: C-reactive protein, HAQ: Health assessment questionnaire disability index, T-SHS: Total van der Heijde modified Sharp score, ES: Erosion Score, DXR: Digital X-ray radiogrammetry, BMD: Bone mineral density.