Figure 2
From: Synoviocytes protect cartilage from the effects of injury in vitro
Synoviocyte gene expression. (A) Gene expression data for synoviocytes in the presence of injured or control cartilage. Data presented as mean relative expression across all time points for each culture condition (± SEM) * denotes statistically significant difference between pairs, + denotes statistically significant difference from baseline, p-value < 0.05. (B) MMP-1 expression was significantly affected by both treatment and duration in culture with a significant increase in expression in synoviocytes cultured with injured cartilage after 48 hours. Synoviocyte gene expression levels are relative to synoviocytes cultured alone. Bars represent mean (± SEM), bars with the same letter for each pathology are not significantly different from each other, significance set at alpha (p-value) = 0.05, n = 6. Main effects or interactions were evaluated in the AOV table with a predictive F-value (Pr > F).