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Table 1 Pre-, intra-, and postoperative factors of deep infection in tumor endoprostheses

From: Deep infection in tumor endoprosthesis around the knee: a multi-institutional study by the Japanese musculoskeletal oncology group

Preoperative

Age (years)

Range

9–86

Mean

34.7

Median

24

Sex

Male

32

Female

25

Comorbidity as infectious risk

Yes

7

No

50

Tumor origin

Primary

51

Metastatic

6

Location

Distal femur

34

Proximal tibia

23

Grade

Low

13

High

38

Extracompartmental tumor extension

Yes

47

No

10

Chemotherapy

38

Radiotherapy

8

Intraoperative extraarticular resection

13

Bone resection length (cm)

Range

10–26

Mean

15.2

Median

14

Number of antibiotics

Single

27

Two

30

Duration of operation (min)

Range

170–1440

Mean

376

Median

305

Intraoperative blood loss (mL)

Range

90–10500

Mean

977.7

Median

585

Extent of partial resection of the quadriceps muscle (femur cases)

Mean

1.8

Median

2

Muscle flap for anterior aspect of the tibia (tibia cases)

Yes

18

No

5

Postoperative

Bad skin condition

20

Surface infection

9

Time from surgery until infection (months)

Range

0–85

Mean

13

Median

4

Loosening

5

Discharge/pus at infection presentation

32

Body temperature at infection presentation (°C)

Range

35.8–40.6

Mean

38.3

Median

38.5

C-reactive protein value at infection presentation (mg/dL)

Range

0.2–45.1

Mean

11.4

Median

9.0

Microbial culture

Staphylococcus aureus

27

Methicillin-resistant S. aureus

10

Staphylococcus epidermidis

10