Differences in osteogenic and apoptotic genes between osteoporotic and osteoarthritic patients

Table 4 Apoptotic genes at least 3-fold upregulated or downregulated in osteoporotic bone tissue

Gen symbol	ID gen(GeneBannk)	Function	Fold change
CD27	NM_001242	TNF Receptor Family	−6.57
CD40	NM_001250	TNF Receptor Family	−7.71
LTBR	NM_002342	TNF Receptor Family	−3.35
TNF	NM_000594	TNF Receptor Family	−16.76
OPG	NM_002546	TNF Receptor Family	−3.52
TRAF4	NM_004295	TRAF Family	−3.72
CRADD	NM_003805	CRAD Family	−4.49
CASP1	NM_033292	Caspase Family	−6.31
CASP4	NM_001225	Caspase Family	−5.34
CASP5	NM_004347	Caspase Family	−5.93
CASP9	NM_001229	Caspase Family	−6.09
CASP10	NM_001230	Caspase Family	−11.93
APAF1	NM_001160	CARD Family	−2.65
CARD8	NM_0149959	CARD Family	−3.45
NOD1	NM_006092	CARD Family	−3.43
NOL3	NM_ 003946	CARD Family	−4.89
RIPK2	NM_003821	CARD Family	−3.96
DAPK1	NM_004938	Death Domain Family	−5.92
BIRC2	NM_001166	IAP family	−3.22
XIAP	NM_	IAP Family	−4.49
BAG1	NM_ 004323	Bcl2-Family	−3.62
BCL2	NM_000633	Bcl2-Family	−6.31
BCL2A1	NM_004049	Bcl2-Family	9.66
BCL2L11	NM_006538	Bcl2-Family	−6.13
BNIP1	NM_001205	Bcl2-Family	2.74
BNIP2	NM_004330	Bcl2-Family	−4.88
ABL1	NM_005157	p53 and DNA damage response	−6.85
BRAF	NM_004333	Anti-apoptosis	−6.55

ISSN: 1471-2474