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Table 2 Clinical characteristics

From: Association of teriparatide adherence and persistence with clinical and economic outcomes in Medicare Part D recipients: a retrospective cohort study

Characteristic

Count

Total Patients

761

  Baseline Clinical Characteristics

 

  Charlson Comorbidity Index*

1.1 (± 1.6)

 

1 [0 - 12]

  Osteoporosis Drug Utilization in Pre-Period n,(%)

353 (46.4%)

    Bisphosphonate n,(%)

283 (80.2%)

    Calcitonin n,(%)

39 (11.0%)

    Selective Estrogen Receptor Modulator (SERM) n,(%)

42 (11.9%)

    Conjugated Estrogen n,(%)

22 (6.2%)

  Fracture in the 6 Month Pre-Period n, (%)

386 (50.7%)

  Fracture in the 12 Month Pre-Period n,(%) **

443 (58.2%)

  Comorbidity (Top 10 Identified) n, (%)†

 

  Other disorders of bone and cartilage (733.)

752 (98.8%)

  Essential hypertension (401.)

546 (71.7%)

  Disorders of lipid metabolism (272.)

529 (69.5%)

  General symptoms (780.)

474 (62.3%)

  Other and unspecified disorders of back (724.)

402 (52.8%)

  Symptoms involving respiratory system and other chest symptoms (786.)

391 (51.4%)

  Other and unspecified disorders of joint (719.)

382 (50.2%)

  Osteoarthritis and allied disorders (715.)

361 (47.44%)

  Other disorders of soft tissues (729.)

333 (43.8%)

  Cataract (366.)

281 (36.9%)

  Post-Period Clinical Characteristics

 

  Fracture in the 12 Month Post-Period n,(%)

222 (29.2%)

  Time Between Index Date and First Fracture (Days)*

200 (± 81)

 

181 [91 - 364]

  Proportion of Days Covered (PDC) Between Index Date and First Fracture*

0.46 (± 0.3)

 

0.38 [0.08 - 1.0]

  Reached Part D Coverage Gap During 12 Month Follow-up Period n, (%)

586 (77%)

  Out of Pocket Cost for All Prescription Claims During 12 Month Follow-up

$2,082 (± $2,189)

  Period*

$991 [$30 - $10,894]

  Out of Pocket Cost for Teriparatide Prescription Claims During 12 Month

$1,247 (± $1,832)

  Follow-up Period*

$228 [$15 - $7,165]

  1. *Mean (M), standard deviation (SD), median, [range].
  2. ** Data for fracture in 12 month pre-period were not available for the entire cohort.
  3. †Based on the first 3 digits of ICD-9 CM code.