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Table 2 Clinical characteristics

From: Association of teriparatide adherence and persistence with clinical and economic outcomes in Medicare Part D recipients: a retrospective cohort study

Characteristic Count
Total Patients 761
  Baseline Clinical Characteristics  
  Charlson Comorbidity Index* 1.1 (± 1.6)
  1 [0 - 12]
  Osteoporosis Drug Utilization in Pre-Period n,(%) 353 (46.4%)
    Bisphosphonate n,(%) 283 (80.2%)
    Calcitonin n,(%) 39 (11.0%)
    Selective Estrogen Receptor Modulator (SERM) n,(%) 42 (11.9%)
    Conjugated Estrogen n,(%) 22 (6.2%)
  Fracture in the 6 Month Pre-Period n, (%) 386 (50.7%)
  Fracture in the 12 Month Pre-Period n,(%) ** 443 (58.2%)
  Comorbidity (Top 10 Identified) n, (%)  
  Other disorders of bone and cartilage (733.) 752 (98.8%)
  Essential hypertension (401.) 546 (71.7%)
  Disorders of lipid metabolism (272.) 529 (69.5%)
  General symptoms (780.) 474 (62.3%)
  Other and unspecified disorders of back (724.) 402 (52.8%)
  Symptoms involving respiratory system and other chest symptoms (786.) 391 (51.4%)
  Other and unspecified disorders of joint (719.) 382 (50.2%)
  Osteoarthritis and allied disorders (715.) 361 (47.44%)
  Other disorders of soft tissues (729.) 333 (43.8%)
  Cataract (366.) 281 (36.9%)
  Post-Period Clinical Characteristics  
  Fracture in the 12 Month Post-Period n,(%) 222 (29.2%)
  Time Between Index Date and First Fracture (Days)* 200 (± 81)
  181 [91 - 364]
  Proportion of Days Covered (PDC) Between Index Date and First Fracture* 0.46 (± 0.3)
  0.38 [0.08 - 1.0]
  Reached Part D Coverage Gap During 12 Month Follow-up Period n, (%) 586 (77%)
  Out of Pocket Cost for All Prescription Claims During 12 Month Follow-up $2,082 (± $2,189)
  Period* $991 [$30 - $10,894]
  Out of Pocket Cost for Teriparatide Prescription Claims During 12 Month $1,247 (± $1,832)
  Follow-up Period* $228 [$15 - $7,165]
  1. *Mean (M), standard deviation (SD), median, [range].
  2. ** Data for fracture in 12 month pre-period were not available for the entire cohort.
  3. Based on the first 3 digits of ICD-9 CM code.