Figure 3

Effect of emphysema on skeletal muscle in terms of thiobarbituric acid reactive substances (TBARS) and carbonyl proteins in hamsters. (A) TBARS levels in muscle homogenates of hamsters treated with 2 different doses of papain. (B) Levels of protein carbonylation in muscle homogenates from control and emphysema hamsters. Results are presented as mean ± standard error of the mean (SEM; n = 8). Statistical differences were detected by one-way ANOVA followed by Bonferroni’s multiple comparison test. Control + saline (CS): animals treated with approximately 0.3 mL of saline only; emphysema 20 mg/mL (E20): animals treated with approximately 0.3 mL of 20 mg/mL papain in saline; and emphysema 40 mg/mL (E40): animals treated with approximately 0.3 mL of 40 mg/mL papain in saline. *p < 0.001 relative to CS, as detected by one-way ANOVA followed by Bonferroni’s multiple comparison test.