Table 1 List of relevant baseline characteristics
Outcome | |||
|---|---|---|---|
Pain | Function | Structure | |
General information | |||
Age | Age | Age | |
Gender | Gender | Gender | |
Activity level in daily life | Activity level in daily life | ||
Psychosocial factors | |||
Pain catastrophizing | |||
Anxiety and Fear | |||
Depression | Depression | ||
Quality of life* | Quality of life* | ||
Information from history | |||
Primary or secondary osteoarthritis | |||
Duration since onset of symptoms indicating knee osteoarthritis | Duration since onset of symptoms indicating knee osteoarthritis | Duration since onset of symptoms indicating knee osteoarthritis | |
Intermittent or constant pain | Intermittent or constant pain | ||
Pain remained constant or varied in the last week | |||
Average daily pain during the last week | Average daily pain during the last week | ||
Walking aid needed (e.g., cane/walker) | |||
Global knee pain** | Global knee pain** | Global knee pain** | |
Waking up with pain | |||
Weight bearing pain | Weight bearing pain | ||
Pain at rest | |||
Pain when going down stairs | |||
Function of knee*** | Function of knee*** | Function of knee*** | |
Pain or reduced function in other joints (hip/spine) | Pain or reduced function in other joints (hip/spine) | ||
Previous history of knee trauma | |||
Previous history of meniscal tear or meniscectomy | |||
Previous history of ACL§ rupture | |||
Previous surgical intervention | |||
Daily dose of pain killers (NSAIDs) | |||
Information from physical examination | |||
BMI | BMI | BMI | |
Physical functional ability; e.g., performance tests of baseline physical ability (e.g., the Timed Up and Go test or a 6-min walking test) | |||
Lab results | |||
Imaging results | |||
Kellgren-Lawrence grading (weight bearing) | |||
Bone marrow lesions | |||
Joint space width | |||
Synovitis (US§§, MRI§§§) | |||
Effusion (US, MRI) | |||
Involved joint compartment (i.e., patellofemoral vs. tibiofemoral vs. combined etc.) | |||
Meniscus tear | |||
Meniscus extrusion | |||
ACL tear | |||
Cartilage abnormalities (MRI) | |||
Malalignment (hip-knee-ankle mechanical axis) | |||
Cartilage volume/thickness in the compartment of interest (MRI) | |||